a bundibugyo virus outbreak in democratic republic of congo's ituri province and neighboring uganda has reached more than 515 cases and 91 deaths, with cdc modeling a high probability of a large outbreak over three months. the outbreak is now expanding into territory controlled by an islamic state-aligned armed group, where burial teams and healthcare workers are being attacked, crippling containment. there is no approved vaccine or treatment, and moderna only just received a $50m commitment to begin preclinical work — a hemorrhagic fever spreading inside an active conflict zone is structurally hard to stop.